Immediate Therapeutic Effects of Diquafosol and Rebamipide in Dry Eye Disease

Korea University Anam Hospital30 enrolled

Overview

This study compares the immediate therapeutic and mucin-secreting effects 30 minutes after instillation of 3% diquafosol and 2% rebamipide in dry eye disease.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Dry Eye Disease (DED)

Interventions

3% diquafosol (right eye) and 2% rebamipide (left eye)DRUG

3% diquafosol was instilled in the right eye and 2% rebamipide in the left eye.

2% rebamipide (right eye) and 3% diquafosol (left eye)DRUG

2% rebamipide was instilled in the right eye and 3% diquafosol in the left eye.

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients 19 years or older * complaint of at least one dry eye symmptom and tear breakup time \< 7 seconds Exclusion Criteria: * Sjogren's syndrome * prescription history of systemic steroids or immunosuppressants * prior ocular surgery within six months of enrollment * treatment with diquafosol or rebamipide eye drops within 2 weeks of enrollment * treatment with punctal plug within 1 month of enrollment * intraocular pressure exceeding 25mmHg * usage of contact lens during the study * active ocular infection * pregnancy or breast-feeding

Locations (1)

Korea University Anam Hospital

Seoul, South Korea