The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air. Participants will provide nasal swabs and have an air sample surveillance device installed in their home.
The purpose of ORCHARDS-AIR is to utilize air surveillance in participant homes in conjunction with individually collected nasal specimens to assess their concordance and evaluate the significance of airborne detection with household transmission of common respiratory pathogens such as influenza and SARS-CoV-2. The researchers postulate that households with documented and probable respiratory pathogen transmission will have higher rates of in-home air surveillance detection. Students with more severe illnesses will be absent more often and spend more time at home, potentially leading to absenteeism being associated with greater air surveillance detections and intrahousehold transmission.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
422
Participants will use a swab to collect nasal specimens
InBio Apollo ambient air sampler to be run in the home for the duration of study participation. Material from the air, like aerosols, dust particles, and other environmental material, are collected on sampler filler material.
University of Wisconsin-Madison
Madison, Wisconsin, United States
RECRUITINGRate of virus detection
Participants will provide nasal swabs, which will be tested for a panel of viruses.
Time frame: Day 0, Day 7, Day 14
Rate of air sampling detection among families with documented transmission
Study team will collect and test air sampler filter for viruses.
Time frame: Day 7, Day 14
Rate of air sampling detection among families without documented transmission
Study team will collect and test air sampler filter for viruses.
Time frame: Day 7, Day 14
Survey of symptoms - day 0
Qualitative survey of participants' symptoms and related activities.
Time frame: Day 0
Survey of symptoms - day 7
Qualitative survey of participants' symptoms and related activities.
Time frame: Day 7
Survey of symptoms - day 14
Qualitative survey of participants' symptoms and related activities.
Time frame: Day 14
Air sampler use survey
Qualitative survey about participants' use of the air sampler.
Time frame: Day 7, Day 14
Number of absences
Participants will self-report whether they were absent from school during the study period.
Time frame: 14 days
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