A New Approach to Hemiplegic Shoulder Pain; Pericapsular Nerve Group Block

Marmara University15 enrolled

Overview

Hemiplegic shoulder pain (HSP) is a common and clinically significant complication after stroke that negatively affects rehabilitation outcomes. It is associated with shoulder subluxation, capsular contracture, spasticity, and central pain mechanisms, leading to pain, limited range of motion, and reduced quality of life. The suprascapular nerve (SSN) block has been shown to be effective for shoulder pain management; however, the glenohumeral joint (GHJ) receives innervation from multiple nerves including the axillary, subscapular, and lateral pectoral nerves. The recently described pericapsular/periarticular nerve group (PENG) block targets these articular branches and may provide analgesia with minimal motor impairment. This study aims to evaluate the effects of ultrasound-guided PENG block in patients with post-stroke hemiplegic shoulder pain, focusing on pain intensity, range of motion, and quality of life outcomes.

Pericapsular/Periarticular Nerve Group (PENG) Block Procedure: The procedure is performed with the patient in the supine position, the affected arm externally rotated and abducted approximately 45 degrees. A high-frequency linear ultrasound probe is placed longitudinally between the coracoid process and the humeral head. After identifying the humeral head, the subscapularis muscle tendon, and the overlying deltoid muscle, an in-plane approach is used to advance a 100-mm needle between the deltoid muscle and the subscapularis tendon under real-time ultrasound guidance. After confirming the needle tip position, a total of 10 mL of 0.25% bupivacaine hydrochloride combined with 4 mg of dexamethasone is injected slowly, ensuring appropriate spread within the targeted pericapsular space. The goal of the block is to provide analgesia for the glenohumeral joint by targeting the articular branches of the axillary, subscapular, and lateral pectoral nerves with minimal motor impairment. No major complications have been reported for this technique in the literature. However, minor complications such as local bleeding, infection, or transient vasovagal reactions may occur.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Shoulder Pain

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 18 and 85 years Presence of hemiplegic shoulder pain with limited shoulder range of motion confirmed by clinical examination Numeric Rating Scale (NRS) pain score ≥ 4 Exclusion Criteria: * Severe deformity or pathology of the shoulder region Complex regional pain syndrome type I Presence of neglect syndrome Grade 4 glenohumeral joint degeneration Coagulopathy or bleeding disorders Fracture on the affected side Secondary pathology on MRI (malignancy or infection) History of allergic reaction to local anesthetic agents or dexamethasone Shoulder intervention or injection within the past 3 months Major psychiatric illness Refusal to participate in the study

Outcomes

Primary Outcomes

Change in Pain Intensity (Numeric Rating Scale, NRS):

NRS is a scale in which the patient gives points between "0" and "10" for the low back and leg pain felt by the patient, "0" = No pain, "10" = The most severe, unbearable pain

Time frame: Baseline, 1 hour, 2 weeks, and 2 months post-intervention. Numeric Rating Scale

Secondary Outcomes

Fugl-Meyer Assessment for Upper Extremity (FMA-UE)

The Fugl-Meyer Upper Extremity Scale is a validated assessment tool designed to evaluate motor recovery after stroke. It includes motor function of the upper limb, wrist, hand movements, coordination, and reflex activity. Each item is scored from 0 to 2 (0 = cannot perform, 1 = partial performance, 2 = normal performance), with a total possible score of 66 points.