Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery

National and Kapodistrian University of Athens50 enrolled

Overview

Inhalational anesthetics, when used in abdominal surgery, offer advantages of lung protection and reduced alveolar inflammation. There is little literature, however, in the comparative use of sevoflurane versus desflurane anesthesia in patients undergoing abdominal robotic-assisted surgery and their effects on lung mechanics.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Respiratory Mechanics Intraoperative

Interventions

Sevoflurane (Volatile Anesthetic)DRUG

Sevoflurane for robotic assisted laparoscopic surgery

Desflurane (volatile anesthetic)DRUG

Desflurane for robotic assisted laparoscopic surgery

Eligibility

Sex: ALLMin age: 18 YearsMax age: 87 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 to 87 years * Undergoing elective robotic-assisted abdominal surgery * ASA physical status I-III Exclusion Criteria: * ASA IV or V * Emergency surgery * Renal insufficiency * Clinically significant respiratory disease * Cardiomyopathy * Uncontrolled hypertension

Locations (1)

Aretaieion University Hospital

Athens, Greece

RECRUITING

Outcomes

Primary Outcomes

airway plateau pressure

Airway plateau pressure (cmH2O) as displayed on the anesthesia ventilator at the specified time points will be recorded for each participant.

Time frame: Perioperatively

Central Contacts

Aliki Tympa, MD,PhD

CONTACT

00306955487575 alikitympa@med.uoa.gr

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.