H. Pylori Infection and AIP Levels

Tanta University300 enrolled

Overview

Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are important for heart health. Changes in lipid levels, such as higher triglycerides and lower "good" cholesterol (HDL), can increase the risk of cardiovascular disease. This study will examine whether H. pylori infection is linked to changes in lipid profiles, especially the Atherogenic Index of Plasma (AIP). AIP is a calculation based on triglycerides and HDL cholesterol that helps predict the risk of heart disease.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

H Pylori Infection Atherogenic Plasma Index

Interventions

urea breath testDIAGNOSTIC_TEST

Participants will undergo a urea breath test to confirm H. pylori infection status. Fasting blood samples will be collected to measure triglycerides and HDL cholesterol, and the Atherogenic Index of Plasma (AIP) will be calculated.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients older than 18 years. * Able to sign the written consent. * Willing to participate in the research and undergo H. pylori testing. Exclusion criteria * Unwilling to participate in the study. * History of severe metabolic disorders. * Taking medications that affect adipose tissue metabolism. * History of gastric surgery.

Locations (1)

Faculty of Medicine

Tanta, Egypt

Outcomes

Primary Outcomes

Atherogenic Index of Plasma (AIP)

AIP is calculated as log10(triglycerides/HDL cholesterol).

Time frame: Baseline (single fasting blood sample at enrollment).

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.