This study compares the effectiveness and safety of two different intralesional treatments for cutaneous warts: a combination of furosemide and digoxin versus polidocanol.
This is a prospective, randomized, single-blind, comparative clinical study to evaluate the efficacy and safety of intralesional combined furosemide-digoxin versus intralesional polidocanol in the treatment of cutaneous warts. Sixty-four adult patients were randomized to receive one of the two treatments every two weeks for a maximum of four sessions. The main goal was to see which treatment was better at completely clearing the warts. The study also looked at side effects and how often the warts came back within six months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
64
Group A (Experimental): Intralesional combined furosemide (10 mg/ml) and digoxin (0.25 mg/ml)
Group B (Active Comparator): Intralesional polidocanol 2%
faculty of Medicine
Banhā, Qalyubia Governorate, Egypt
Complete Clinical Response
100% clearance of the treated wart at the end of the treatment period.
Time frame: Up to 8 weeks
Incidence and Severity of Adverse Effects
Assessment of side effects such as pain, erythema, edema, and ulceration.
Time frame: Throughout the treatment period (up to 8 weeks)
Recurrence Rate
Rate of wart recurrence at the 6-month follow-up visit
Time frame: 6 months post-treatment
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