Through longitudinal analysis of dynamic changes in DMN functional connectivity before and after sensory training intervention, combined with pain behavioral and functional improvement indicators, this study systematically reveals the central neural remodeling patterns in CNLBP and establishes an objective efficacy evaluation system based on multimodal imaging.
This phase of the research aims to elucidate the neuroplasticity mechanisms induced by CNLBP treatment, providing a theoretical basis for the future development of personalized rehabilitation protocols based on brain network subtypes, ultimately achieving the clinical goals of reducing pain recurrence rates and improving long-term prognosis in patients.
Study Type
OBSERVATIONAL
Enrollment
40
Functional connectivity analysis of brain networks based on functional magnetic resonance imaging (fMRI) technology
VAS
The Visual Analogue Scale (VAS) was used to assess the severity of low back pain, with 0 indicating no pain and 10 indicating unbearable severe pain.
Time frame: After 4 weeks of treatment
JOA
The Japanese Orthopaedic Association (JOA) efficacy assessment criteria for low back disorders were applied to evaluate lumbar function.
Time frame: After 4 weeks of treatment
MRI
Magnetic resonance imaging was used to assess the effects of treatment on brain networks.
Time frame: After 4 weeks of treatment
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