The goal of this clinical study is to learn whether a physician-nurse collaborative intervention guided by an Intelligent Hypoglycemia Risk Early-Warning System can reduce hypoglycemia and improve glycemic control in hospitalized adults with type 2 diabetes receiving intensive insulin pump therapy. The study also aims to understand how risk-stratified management influences the time needed to reach glycemic targets. The main questions this study aims to answer are: 1. Does the physician-nurse collaborative intervention reduce the incidence of hypoglycemia, particularly level 2 and symptomatic hypoglycemia? 2. Does this intervention help patients reach their glycemic targets sooner during intensive insulin pump therapy? 3. What differences in outcomes are observed between patients classified as high-risk and low-risk by the Intelligent Hypoglycemia Risk Early-Warning System? Participants will: 1. Receive either standard insulin pump therapy alone or insulin pump therapy combined with the physician-nurse collaborative intervention 2. Undergo hypoglycemia risk assessment using the Intelligent Early-Warning System 3. Receive individualized insulin dose adjustments, intensified glucose monitoring, and tailored hypoglycemia education based on their risk category 4. Be monitored for hypoglycemic events and time to achieve glycemic targets during hospitalization This study will compare the collaborative intervention with standard care to evaluate its effectiveness in preventing hypoglycemia and accelerating glycemic stabilization among hospitalized patients with type 2 diabetes.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
1,255
Participants in this arm will receive standard insulin pump therapy combined with a physician-nurse collaborative intervention guided by an Intelligent Hypoglycemia Risk Early-Warning System. The intervention includes individualized insulin dose adjustment, intensified glucose monitoring, risk-stratified hypoglycemia prevention strategies, targeted education, and nurse follow-up based on real-time risk alerts.
Participants in this arm will receive standard insulin pump therapy and usual nursing care according to routine hospital practice, without the use of the Intelligent Hypoglycemia Risk Early-Warning System or the physician-nurse collaborative intervention.
Third Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
Incidence of Hypoglycemia
The proportion of participants experiencing hypoglycemia, defined as blood glucose \< 3.9 mmol/L. Hypoglycemia will be further classified into level 1, level 2, level 3, symptomatic, and asymptomatic categories based on international clinical criteria.
Time frame: From the date of randomization until hospital discharge, assessed up to 14 days.
Time to Glycemic Target
Time required for participants to reach predefined glycemic targets during insulin pump therapy. Glycemic targets are defined as fasting blood glucose 4.4-7.0 mmol/L and 2-hour postprandial glucose \< 10.0 mmol/L.
Time frame: From the date of randomization until achievement of predefined glycemic targets, assessed up to 14 days.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.