Sensitivity to Ovarian Hormones and Depression in Adolescents

N/ANot Yet RecruitingNCT07317895

University of Calgary94 enrolled

Overview

The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is: Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Depressed

Eligibility

Sex: FEMALEMin age: 12 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Assigned female at birth, at least 1 year post-menarche, naturally cycling, history of depression or symptoms of depression, and able to read and write in English. Exclusion Criteria: * Pregnant or taking any hormonal or cycle altering medications/devices.

Locations (1)

University of Calgary

Calgary, Alberta, Canada

Outcomes

Primary Outcomes

Identification ovarian hormone affect sensitivity

Identify depressed adolescents assigned female at birth with depressed affect sensitivity to changes in ovarian hormones across the menstrual cycle.

Time frame: 90 days

Central Contacts

Whitney Hindmarch, PhD

CONTACT

587-534-7260 whitney.hindmarch@ucalgary.ca

Data from ClinicalTrials.gov

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