Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
42
The exercise consists of running on a treadmill at 90% of maximum aerobic speed (MAS) for 30 minutes, followed by 12% increments every 5 minutes, until exhaustion (a "time-to-exhaustion" type of exercise).
Chu Saint-Etienne
Saint-Etienne, France
RECRUITINGDuration of deep slow-wave sleep
Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA).
Time frame: Once a month for 3 months
Assessment of core temperature
Assessment of core temperature until the end of the sleep period will be measured using gastrointestinal telemetric pills (eCelsius, Bodycap®, France).
Time frame: Once a month for 3 months
Evaluation of autonomic nervous system thermoregulation
Evaluation of autonomic nervous system thermoregulation through time-domain (R-R intervals in ms)
Time frame: Once a month for 3 months
Evaluation of autonomic nervous system thermoregulation
Evaluation of autonomic nervous system thermoregulation through frequency- domain parameters (in Hz)
Time frame: Once a month for 3 months
Complementary sleep evaluation
Complementary sleep evaluation through analysis of duration of N1, N2, and REM stages (in Percentage of Total Sleep Time)
Time frame: Once a month for 3 months
Complementary sleep evaluation
Complementary sleep evaluation through characteristics of slow waves present in N3 (amplitude in microvolts)
Time frame: Once a month for 3 months
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