Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adults

Inclusion Criteria: * Adults aged 40 to 65 years. * Individuals with no history of cerebrovascular, cardiovascular, or neurological diseases. * Individuals who have signed the informed consent form and voluntarily agreed to participate in the study Exclusion Criteria: * Individuals with a history of cerebrovascular, cardiovascular, or neurological diseases (e.g., stroke, angina, epilepsy). Individuals currently taking medications that may affect cerebral blood flow (such as antihypertensive agents or antidepressants). Individuals with skin diseases or lesions that make it difficult to apply heat or acupressure devices to the carotid artery region, and individuals who are pregnant or breastfeeding. Individuals with a history of seizures. Individuals who have participated in clinical studies two or more times in the same year, or who have participated in another clinical study within the past 6 months. Individuals who, in the judgment of the principal investigator or sub-investigator, have clinically significant findings that make them unsuitable for participation in this study.