To establish evidence that cold ischemia, achieved through the use of ice slush, can improve the recovery from ischemia on the operated kidney in patients undergoing robot-assisted partial nephrectomy.
Randomly dividing the study cohorts into two groups. One group undergoing cold ischemia partial nephrectomy and the other undergoing warm ischemia partial nephrectomy. Comparing the short-term renal function recovery between the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
310
During the surgical procedure, employing ice to achieve local hypothermia in the kidneys.
Not applying local hypothermia to the kidneys during the surgical procedure
651 Dongfeng Road East, Yuexiu District, Guangzhou, P.R. China Sun Yat-sen University Cancer Center；
Guangzhou, Guangdong, China
RECRUITINGRecovery from ischemia
(%GFR saved)/(%parenchymal mass preserved)
Time frame: 1-12 months after surgery
surgical duration
The duration of the surgery
Time frame: Intraoperative
surgical complications
Intraoperative and postoperative complication incidence rate
Time frame: 1-12 months after surgery
The extent of decline in the long-term GFR (month13-24) on the operated kidney compared to the new baseline GFR(months 1-12).
Postoperative short-term GFR(months 1-12) minus long-term GFR(month13-24)
Time frame: up to 2 years after surgery
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