The Application of Extracellular Vesicle Detection in Gastric Juice Based on Metamaterial Sensing in the Diagnosis of Gastric Cancer and Related Diseases

N/ANot Yet RecruitingNCT07332104

Beijing Friendship Hospital100 enrolled

Overview

After obtaining informed consent from the patients, all the medical history and treatment records of the patients who underwent gastroscopy since the onset of the disease, as well as gastric fluid samples, including laboratory and imaging data, were collected and recorded. The medical history and treatment records and gastric fluid samples were analyzed.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Gastric Cancer (GC)Gastric Cancer (Diagnosis)

Interventions

In vitro surface plasmon resonance detectionDIAGNOSTIC_TEST

Gastric juice from patients was removed for isolation of extracellular vesicles and surface plasmon resonance detection in vitro

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients underwent gastroscopy and treatment at the Endoscopy Center of Beijing Friendship Hospital, Capital Medical University, and received pathological biopsy. * Previous gastroscopy suggested the possibility of lesions. * No previous history of gastrointestinal cancer. Exclusion Criteria: * Patients could not cooperate with the examination or had contraindications to endoscopy. * Previous history of gastrointestinal tumors, gastrointestinal surgery, physical and chemical injuries of the gastrointestinal tract. * Severe bile reflux. * Take simethicone and other defoaming agents before examination. * Patients with serious diseases of heart, lung, kidney, brain, blood and other important organs.

Outcomes

Primary Outcomes

Surface plasmon resonance(SPR) detection of extracellular vesicles in gastric juice of patients with gastric cancer has large shift and spectral changes

Time frame: baseline

Central Contacts

Hao-Su Zhan, Dr.

CONTACT

13565915192 1509082764@qq.com

Data from ClinicalTrials.gov

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