New Technique of End-to-Side Two-Layered Duct-to-Mucosa Pancreaticojejunostomy With Omental Wrapping and Glue (Glubran 2) During Laparoscopic Whipple Operation

Theodor Bilharz Research Institute30 enrolled

Overview

Following pancreaticoduodenectomy, omental flaps around the pancreatic anastomosis and adhesive glue can lower the risk of pancreatic fistula, post-pancreatectomy bleeding, and delayed gastric emptying. The overall morbidity following pancreaticoduodenectomy can be decreased with this straightforward and efficient treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Periampullary Carcinoma Resectable

Interventions

Pancreaticojejunostomy without omental patchPROCEDURE

A laparoscopic pancreaticoduodenectomy with pylorus preservation was performed on each patient. A pancreatojejunostomy was created and not fixed with an omental patch or glue.

Pancreaticojejunostomy with omental patch and gluePROCEDURE

A laparoscopic pancreaticoduodenectomy was performed on each patient. A pancreaticojejunostomy was fixed with glue to secure the anastomosis. The greater omentum was separated longitudinally over an avascular zone, and one or two omental branches of the gastroepiploic arteries were preserved using pedicle omental flaps. The omentum was rolled up and secured with glue.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Resectable tumors of the periampullary region Exclusion Criteria: * Pancreatic or duodenal tumors * Irresectability criteria (such as metastases, ascites, or arterial vascular invasion)

Locations (1)

Theodor Bilharz Research Institute

Giza, Egypt

Outcomes

Primary Outcomes

The rate of pancreatic fistula after pancreaticoduodenectomy

Time frame: 4 weeks postoperative

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.