The goal of this clinical trial is to determine the prevalence of exocrine pancreatic insufficiency (EPI) in a population of pediatric and adult participants with Alagille Syndrome (ALGS) post liver transplant. During the study, participants will: * Consume a high fat diet * Keep a diary of their abdominal signs and symptoms, and stool frequency and consistency * Collect stool for laboratory testing
Study Type
OBSERVATIONAL
Enrollment
30
coefficient of fat absorption
Children's Hospital Colorado - Research Institute
Aurora, Colorado, United States
RECRUITINGHassenfeld Children's Hospital at NYU Langone
New York, New York, United States
RECRUITINGCincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
NOT_YET_RECRUITINGResearch Institute at Nationwide Children's Hospital
Columbus, Ohio, United States
NOT_YET_RECRUITINGOregon Health & Science University
Portland, Oregon, United States
NOT_YET_RECRUITINGVanderbilt University Medical Center
Nashville, Tennessee, United States
RECRUITINGPediatric GI of El Paso
El Paso, Texas, United States
RECRUITINGSeattle Children's Hospital - Research Institute
Seattle, Washington, United States
NOT_YET_RECRUITINGDietary fat absorption
Dietary fat absorption is measured by calculating the percent of fat absorption (0-100%). Higher percentage of fat absorption indicates good fat absorption.
Time frame: At the completion of the 72-hour stool collection period
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