Reticulocyte Parameters as Early Indicators of Bone Marrow Erythropoietic Activity in Chronic B Lymphoproliferative Neoplasms

N/ANot Yet RecruitingNCT07337967

Huda Ahmed Abdelsabour Abdelwahab120 enrolled

Overview

Reticulocyte parameters as early indicators of bone marrow erythropoietic activity in chronic B lymphoproliferative neoplasms

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

B Chronic Lymphocytic Leukemia

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Newly diagnosed adult patients with Chronic B LymphoPoliferative neoplasm according to WHO classification. Exclusion Criteria: 1\) Patients received chemotherapy. 1. Patients with Active bleeding 2. Patients with recent blood transfusion (less than 2 weeks). 3. Patients on haematinics or vitamin B 12 therapy

Outcomes

Primary Outcomes

Reticulocyte count

Absolute peripheral blood reticulocyte count measured in patients with chronic B-cell lymphoproliferative disorders (CLPDs). Unit of Measure: ×10⁹/L

Time frame: 1 year

Reticulocyte percentage

Percentage of reticulocytes among total red blood cells in peripheral blood of patients with CLPDs. Unit of Measure: %

Time frame: 1 year

Immature reticulocyte fraction (IRF)

Proportion of immature reticulocytes in peripheral blood measured in patients with CLPDs. Unit of Measure: %

Time frame: 1 year

Data from ClinicalTrials.gov

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