Chest CT Scan in Pulmonary Mucormycosis: Prognostic Value

University Hospital, Strasbourg, France80 enrolled

Overview

Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pulmonary Mucormycosis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 18 years or older * Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025 * With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria * Having undergone at least one CT scan including the thoracic region Exclusion Criteria: * No CT scan including the thoracic region * No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)

Locations (1)

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

Outcomes

Primary Outcomes

Death rate in patients with probable or proven invasive Mucorales infection

Death rate at day 15 in patients with probable or proven invasive Mucorales infection

Time frame: Day 15 after infection