The goal of this clinical trial is to evaluate the clinical efficacy and safety of YiWei Jiaohuang Ointment in treating gastrointestinal bleeding associated with oral antithrombotic therapy. The main question it aims to answer is: Does Yiwei JiaoHuang Ointment accelerate the conversion to negative results in fecal occult blood tests among patients with gastrointestinal bleeding associated with antithrombotic therapy? Researchers will compare use rabeprazole alone as routine therapy to see if Yiwei JiaoHuang Ointment can accelerate the conversion to negative results in fecal occult blood tests. Participants will : Take Yiwei JiaoHuang Ointment every day for 2 weeks. Return to the hospital for a fecal occult blood test after 3 days, 1 week, and 2 weeks of medication.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Yiwei Jiaohuang Onitment consists of four Chinese herbs: 3g of Duyiwei(Lamiophlomis Herb), 3g of raw Da Huang(Rhubarb Root and Rhizome (Unprocessed)), 6g of Bai Ji(Bletilla Rhizome) and 10g of Ejiao (donkey-hide gelatin). Prepared as ointment, patients should take one dose daily in the morning on an empty stomach for 2 weeks.
Rabeprazole Enteric-Coated Tablets10mg once a day for 2 weeks
China-Japan Friendship Hospital
Beijing, China
The rate of negative fecal occult blood test results in the two groups of patients after 2 weeks of intervention.
Time frame: two weeks of intervention
Time required for fecal occult blood to turn negative in two groups of patients.
Time frame: two weeks of intervention
The rate of negative fecal occult blood test results in the two groups of patients after 3 days of intervention.
Time frame: 3 days of intervention
The rate of negative fecal occult blood test results in the two groups of patients after one week of intervention.
Time frame: one week of intervention
Changes in hemoglobin levels in two groups of patients after 2 weeks of intervention.
Time frame: two weeks of intervention
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