The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Roasted, lightly salted, pistachio kernels (no shell)
Public Health Research Center: Clinical Exercise Research Center
Columbia, South Carolina, United States
RECRUITINGresting metabolism
resting metabolic rate (RMR) and substrate utilization (RER) via indirect calorimetry
Time frame: Day 0 and Day 5
exercise metabolic flexibility
substrate metabolism (RER; indirect calorimetry) throughout a submaximal, graded exercise test
Time frame: Day 0 and Day 5
post-exercise metabolism
Energy expenditure and substrate metabolism (RER) measured at 0, 30, 60, 90min post-exercise via indirect calorimetry
Time frame: Day 0 and Day 5
Caloric Intake
Average calorie intake (kcal) via 24-hr diet record
Time frame: Day 0 and Day 4
Carbohydrate Intake
Average carbohydrate intake (grams) via 24-hr diet record
Time frame: Day 0 and Day 4
Protein Intake
Average protein intake (grams) via 24-hr diet record
Time frame: Day 0 and Day 4
Fat Intake
Average fat intake (grams) via 24-hr diet record
Time frame: Day 0 and Day 4
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.