The goal for this clinical trial is to compare acute immune effects of three nutraceutical ingredients and blends to a placebo.
The goal for this clinical trial is to compare acute immune effects of anthocyanin-rich botanical extracts and blends to a placebo. Stem cell mobilization and homing will be evaluated through monitoring of changes to the numbers of various types of stem cells in the blood circulation. The testing will show whether consuming the active test products lead to changes in stem cell numbers in circulation above the normal circadian changes for each participant. The normal circadian changes are documented on the clinic visit where placebo is consumed. Several different stem cell populations will be evaluated using flow cytometry.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
48
0.5 grams
0.5 grams
0.5 grams
NIS Labs
Klamath Falls, Oregon, United States
Stem cell surveillance
Changes to the number of stem cells in the blood circulation (number of cells per mL blood). Data is collected on the following types of stem cells: CD45dimCD34+CD309+, CD45dimCD34+CD309-, CD31++CD34-, CD45-CD90+.
Time frame: Baseline, 1 hour, 2 hours after consumption
Serum cytokine levels
Time frame: Baseline, 1 hour, 2 hours after consumption
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Placebo (white rice-based)