Efficacy of Immediate Versus Staged Complete Revascularization in Patients With NSTE-ACS and Multivessel Disease (FUTURE II)

Inclusion Criteria: 1. Age: 18 years or older. 2. Patients with intermediate-to-high risk NSTE-ACS who meet the diagnostic criteria specified in current guideline, complicated by multivessel coronary artery disease, and have successfully undergone PCI for the culprit vessel. 3. PCI within 72 hours of diagnosis. 4. Accompanied by multivessel disease: defined as at least one non-culprit artery that meets the following conditions: a diameter of ≥2.5 mm by visual inspection, which can be successfully subjected to PCI, and the most severe diameter stenosis rate by visual inspection is at least 70% or positive coronary physiology testing. 5. Sign an informed consent form before participating in the study. Exclusion Criteria: 1. Have received thrombolytic treatment. 2. Cardiogenic shock or SBP\< 90 mmHg. 3. Patients in whom the culprit vessel cannot be clearly identified. 4. Left main coronary artery lesion, non-infarct-related arteries are CTO lesions or severely calcified lesions, complex lesions that require the use of special devices such as rotational ablation/laser. 5. Previous PCI within the past 1 month or previous coronary artery bypass graft (CABG). 6. Accompanied by other diseases that lead to an expected survival time of ≤ 12 months. 7. Patients with other serious diseases such as severe renal insufficiency (creatinine clearance value \<30ml/min), hepatic insufficiency, thrombocytopenia (≤50\*109/L). 8. Patients with severe valvular disease, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and primary pulmonary hypertension. 9. Not suitable for clinical study: 1. Have enrolled in the other clinical studies that may affect the outcome assessment of this study. 2. Pregnant and lactating women. 3. Known allergy to the drugs that may be used in the study. 4. Unable to comply with the trial protocol or follow-up requirements; or the investigator believes that participation in the trial may put the patient at greater risk.