Effects of Short-term Intensive Statin Therapy on Lipid Levels

Inclusion Criteria: * Age ≥ 18 years; * Diagnosis of ischemic stroke (within 14 days of onset) confirmed by cranial CT/MRI; or imaging-confirmed intracranial/extracranial atherosclerotic stenosis (stenosis rate ≥ 50%); * Intensive statin therapy (e.g., atorvastatin 40-80 mg/day or rosuvastatin 20 mg/day) initiated within 24 hours of admission, with a planned continuous application for at least one week; * Signed informed consent form. Exclusion Criteria: * Use of statin therapy within 1 week prior to admission; * Receiving other lipid-lowering treatments; * Presence of other serious comorbidities (e.g., malignant tumors, end-stage heart failure) with an expected survival of \<1 year; * Pregnant or lactating women; * Participation in other drug clinical trials within 3 months; * Other conditions deemed unsuitable by the investigator.