VCMX, PRF and SCTG Treatment in the Gingival Recessions

Bulent Ecevit University60 enrolled

Overview

Comparison of Volume-Stable Collagen Matrix, Platelet-Rich Fibrin, and Subepithelial Connective Tissue Graft in the Treatment of Multiple Adjacent Gingival Recessions: A Parallel-Group, Randomized, Controlled Clinical Trial

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Gingival Recession, Localized

Interventions

Volume-Stable Collagen MatrixBIOLOGICAL

Volume-Stable Collagen Matrix

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion criteria were as follows: 1. ≥2 mm buccal recessions affecting ≥2 adjacent maxillary teeth; 2. systemically and periodontally healthy; 3. non-smokers; 4. Miller Class I-II (no interproximal attachment or CEJ loss); 5. probing depth (PD) \<3 mm; 6. GT ≥1 mm; 7. KGW ≥2 mm; 8. identifiable CEJ; 9. full-mouth plaque index (PI) \<20%(O'Leary et al., 1972) and gingival index (GI) score of 0(Löe, 1967) and 10. vital teeth to be treated. Exclusion criteria included: 1. smokers; 2. caries/restorations/abrasions in the treated area, furcation involvement; 3. contraindications to surgery; 4. pregnancy or lactation; 5. medications compromising healing; 6. surgery in the same region within 2 years; 7. bleeding disorders; 8. requirement for antibiotic prophylaxis; and 9. collagen allergy.

Locations (1)

Ankara Yıldırım Beyazit University

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Percentage of Complete Root Coverage

Percentage of CRC will be calculated as: (number of teeth achieving complete root coverage) ÷ (total treated teeth)\] × 100

Time frame: 12 Months

Secondary Outcomes

Percentage of Mean Root Coverage

Percentage of root coverage will be calculated as: Percentage of root coverage: \[(preoperative recession depth - postoperative recession depth) ÷ preoperative recession depth\] × 100

Time frame: 12 months

Recession depth

RD will be measured from the cemento-enamel junction (CEJ) to the gingival margin and reported in millimeters (mm).

Time frame: 12 month

Probing depth

Probing depth will be measured from the gingival margin to the base of the sulcus and reported in millimeters (mm).

Time frame: 12 months

Clinical attachment level

Clinical attachment level will be measured from the cemento-enamel junction to the sulcus base and reported in millimeters (mm).

Time frame: 12 months

Keratinized gingiva width

KGW will be measured from the mucogingival junction to the gingival margin and reported in millimeters (mm).

Time frame: 12 months

Gingival Thickness

Gingival thickness (GT) will beevaluated at the mid-facial aspect, 2 mm apical to the gingival margin in the attached gingiva or alveolar mucosa, using a #15 endodontic spreader (Bahadır Diş, Istanbul, Turkey) with a rubber stopper under local anesthesia and reported in milimeters.

Data from ClinicalTrials.gov

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