This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.
Study Type
OBSERVATIONAL
Enrollment
518
Endovascular therapy performed as part of routine clinical care for acute basilar artery occlusion, including mechanical thrombectomy with stent retriever and/or aspiration. Rescue angioplasty and/or intracranial stenting may be used at the operator's discretion. Peri-procedural management and concomitant medical therapy follow local standard practice.
Xuanwu Hospital
Beijing, Beijing Municipality, China
Proportion of Patients Achieving mRS 0-3 at 90 Days
The modified Rankin scale (range, 0 \[no symptoms\] to 6 \[death\]). Higher scores mean a worse outcome.
Time frame: 90 days
Ordinal Shift analysis of mRS at 90 days
The modified Rankin scale (range, 0 \[no symptoms\] to 6 \[death\])
Time frame: 90 days
Rate of All-Cause Mortality at 90 Days
Death from any cause within 90 days.
Time frame: 90 days
Rate of Symptomatic Intracranial Hemorrhage
Time frame: 24 (-2/+12) hours
Proportion of Patients Achieving mRS 0-3 at 1 year
The modified Rankin scale (range, 0 \[no symptoms\] to 6 \[death\]). Higher scores mean a worse outcome.
Time frame: 1 year
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