Predictive Value of a Rectal Swab With Detection of Enterobacteria (ESBL-E), Carbapenemases, and High-level Cephalosporinase (HLC) on the Risk of Infections With C3G-resistant Enterobacteria

University Hospital, Strasbourg, France1,000 enrolled

Overview

The objective of the research is to evaluate the value of testing for ESBL carriage by rectal swab to predict the risk of ESBL-producing Enterobacteriaceae infections in intensive care.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Infections, Enterobacteriaceae

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients (≥ 18 years old) * Who have been in medical or surgical intensive care at Strasbourg University Hospitals (between January 1, 2024, and January 1, 2025) * Who have undergone rectal screening for carriage of ESBL/HLC/carbapenemase-producing Enterobacteriaceae Exclusion Criteria: * Refusal to participate in the study

Locations (1)

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

Strasbourg, France

RECRUITING

Outcomes

Primary Outcomes

Negative predictive value of a negative rectal swab for the risk of infection with ESBL-producing Enterobacteriaceae

The negative predictive value (NPV) answers the following question: When the test is negative, what is the probability that the person will not develop an infection with these resistant bacteria? For example: * Out of 100 people with a negative smear test, * if 95 never develop an infection, then the negative predictive value is 95%.

Time frame: Up to 12 months

Central Contacts

baptiste Hoellinger, MD

CONTACT

33 3 69 55 05 45 baptiste.hoellinger@chru-strasbourg.fr

Data from ClinicalTrials.gov

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