Effectiveness of Large Language Model-Based Chatbot in Improving HPV Vaccine Awareness, Intention and Vaccination Rates

N/ANot Yet RecruitingNCT07351604

Xiamen University36,000 enrolled

Overview

This is an interventional study targeting parents of junior high school girls and female university students. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates. The secondary objectives are to evaluate the effectiveness in improving vaccine awareness and vaccination intention. All participants will be enrolled and randomly assigned to four groups: (1) vaccine chatbot plus scientific videos, (2) vaccine chatbot only, (3) scientific videos only, and (4) a control group (no intervention). The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions. The scientific videos will cover content related to HPV vaccine safety, efficacy, and other relevant information. The study will compare changes in HPV vaccine awareness, vaccination intention, and vaccination behavior between the intervention groups and the control group after the intervention to evaluate whether the three intervention strategies enhance HPV vaccine awareness, vaccination intention, and vaccination uptake.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

36,000

Conditions

HPV Vaccination Rates HPV Vaccine Awareness

Eligibility

Sex: ALLMin age: 9 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Parents of junior high school girls / Female university students. 2. Possess an electronic device with QR code scanning capability. 3. The daughters / female university students have no contraindications to HPV vaccination. 4. No mental disorders or visual/reading impairments; able to cooperate with and implement the corresponding intervention activities. 5. Have provided informed consent and are willing to participate in the study. Exclusion Criteria: \-

Outcomes

Primary Outcomes

HPV vaccination rates for eligible parents' daughters and female university students in all groups before and after the intervention

Whether participants' daughters and female university students get vaccinated against HPV or have an appointment for vaccination, measured by self-report and validated by vaccination information system

Time frame: Baseline, two weeks and six months

Secondary Outcomes

HPV vaccine awareness for eligible parents' daughters and female university students in all groups before and after the intervention

A questionnaire consisting of 11 questions related to HPV vaccines will be used to investigate the awareness of HPV vaccines.Total knowledge score is calculated based on the number of questions answered correctly by the participants and the higher scores mean a better outcome.

Time frame: Baseline and two weeks

HPV vaccination intention for eligible parents' daughters and female university students in all groups before and after the intervention

Parents' willingness to vaccinate their daughters against HPV and and female university students' willingness to vaccinate themselves, measured using a five-point Likert scale from "not willing at all" to "strongly willing"