Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players. Sixty participants were randomized to experimental (plyometrics twice weekly) or control (routine volleyball) groups. Blood sampling occurred at baseline; days 2, 4, and 6; and weeks 1, 2, 4, 6, and 8.
Intervention adapted from James \& Robert (2015). Experimental group completed progressive lower-body plyometrics twice weekly (Monday/Wednesday) over eight weeks with warm-up and cool-down. Exercises included squat jump; jump to box (30 cm); tuck jump; split squat jump; lateral hurdle jump (50 cm); zigzag jump; single-leg tuck jump; and depth jump (80 cm). Control group continued routine volleyball activities and did not perform low/medium/high-intensity plyometrics. Primary biomarker (serum CPK) assessed via CK-NAC optimized IFCC method; serum creatinine by modified Jaffe's method. Two-way ANOVA with Bonferroni post hoc used. Findings: CPK increased from day 2, peaked day 4, stabilized to week 2, then declined toward baseline by week 8; creatinine remained stable.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
60
Twice-weekly sessions (Mon/Wed) for 8 weeks; exercise menu and dosing per Table 1 (intensity, rest, and jumps/set).
Dr. Mariam Salem
Jeddah, Saudi Arabia
Serum CPK (U/L)
change from baseline at day 2, day 4, week 1, week 2, week 4, week 6, week 8
Time frame: Baseline; 2, 4, 6 days; 1, 2, 4, 6, 8 weeks
Serum creatinine (mg/dL)
change from baseline over same time points
Time frame: Baseline; 2, 4, 6 days; 1, 2, 4, 6, 8 weeks
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