Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism

Alexandria University40 enrolled

Overview

This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CT pulmonary angiography and followed up with sllep study to asses the effect of sleep related breathing disorderon the recurrence of emboli.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pulmonary Embolism Sleep Apnea Syndrome (OSAS)

Interventions

polysomnographyDIAGNOSTIC_TEST

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age≥18years. * Objectively confirmed acute pulmonary embolism by computed tomography pulmonary angiography (CTPA). * Hemodynamically stable or clinically stabilized within 72 hours of admission. .Ability to provide informed consent. Exclusion Criteria: .Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation. * Pregnancy

Locations (1)

Faculty of Medicine

Alexandria, Egypt, Egypt

Outcomes

Primary Outcomes

Pulmonary embolism recurrence

ocuurence of pulmonary embolism during the follow up period confirmed by CTPA

Time frame: 12 months

Recurrence of Pulmonary Embolism

occurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA

Time frame: ONE YEAR

Data from ClinicalTrials.gov

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