Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter

Phase 4CompletedNCT07359508

All India Institute of Medical Sciences146 enrolled

Overview

effect of propofol vs desflurane on ONSD

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

146

Conditions

Propofol Target-controlled Infusion Desflurane Optic Nerve Sheath Diameter

Interventions

DesfluraneDRUG

In the D group, anesthesia was maintained with oxygen/air (40:60), desflurane, fentanyl and vecuronium

Propofol (Group P)DRUG

In the P group, anesthesia was maintained with oxygen/air (40:60), propofol infusion @50 to 100mcg/kg/min, fentanyl and Vecuronium

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient aged 18-60 years ASA grade I or II scheduled for elective laparoscopic cholecystectomy Exclusion Criteria: * patients with ophthalmological and cerebrovascular diseases, systemic infections, psychiatric disorders, pregnancy, Intracranial space occupying lesion, abnormal liver/kidney functions prior myocardial infarction.

Locations (1)

AIIMS

Raebareli, Uttar Pradesh, India

Outcomes

Primary Outcomes

Optic nerve sheath diameter(ONSD)

ONSD will be measured in the operation thetaer

Time frame: before induction, introperative period for every 10 minutes

Data from ClinicalTrials.gov

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