The aim of this pilot study is to estimate the effect size of changing the glucose-fructose ratio from 1:0.5 to 1:1 on exogenous carbohydrate oxidation rates during exercise, which can be used to power a future definitive study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
10
Glucose and fructose ingested in solution in a one-to-one ratio (135 grams per hour for 3 hours during exercise)
Glucose and fructose ingested in solution in a two-to-one ratio (135 grams per hour for 3 hours during exercise)
University of Bath
Bath, Bath, United Kingdom
RECRUITINGExogenous carbohydrate oxidation rate (g/h)
Total exogenous carbohydrate oxidation rate (g/h) over 180 minutes
Time frame: 180 minutes
Peak exogenous carbohydrate oxidation rate (g/h)
Highest recorded exogenous carbohydrate oxidation rate (g/h)
Time frame: 180 minutes
Whole-body carbohydrate oxidation rate (g/h)
Total whole-body carbohydrate oxidation rate (g/h)
Time frame: 180 minutes
Endogenous carbohydrate oxidation rate (g/h)
Total endogenous carbohydrate oxidation rate (g/h)
Time frame: 180 minutes
Whole-body fat oxidation rate (g/h)
Total whole-body fat oxidation rate (g/h)
Time frame: 180 minutes
Blood lactate concentrations (mmol/L)
Mean blood lactate concentrations over 180 minutes
Time frame: 180 mninutes
Blood glucose concentrations (mmol/L)
Mean blood glucose concentrations (mmol/L) over 180 minutes
Time frame: 180 minutes
Ratings of gut comfort (arbitrary units)
Mean ratings of gut comfort (arbitrary units) over 180 minutes
Time frame: 180 minutes
Ratings of perceived exertion (arbitrary units)
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Mean ratings of perceived exertion (arbitrary units) over 180 minutes
Time frame: 180 minutes