Clear Cell Chondrosarcoma in Italy

N/AActive Not RecruitingNCT07360964

Istituto Ortopedico Rizzoli77 enrolled

Overview

Clear cell chondrosarcoma of bone is considered a low-grade malignant tumor in the last WHO classification of soft tissue and bone tumors; however, it is reported that recurrences and metastasis can occur. Considering the uncertain prognosis of this rare tumor, with some cases that historically seems to pursue a bad prognosis, we decided to collect all the Italian cases of clear cell condrosarcoma, in order to better understand its natural history and prognosis.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Chondrosarcoma

Interventions

Molecular studiesGENETIC

Molecolar studies to define possible prognostic parameters

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male and female patients with diagnosis of clear cell chondrosarcoma and chondrosarcoma with a clear cell component treated from 01 Jan 1982 to 31 Dec 2023 * Information available (date of primary tumor diagnosis, local treatments, systemic treatment, response to systemic treatment, date of progression) and date and status at last follow-up * Imaging studies available for revision * Histological slides available for revision Exclusion Criteria: * \- Diagnosis different from clear cell chondrosarcoma or chondrosarcoma with a clear cell component; * Absence of radiological and/or clinical data

Locations (1)

IRCC Rizzoli Orthopedic Institute

Bologna, Italy

Outcomes

Primary Outcomes

Prognostic accuracy

Ability of the model to predict overall survival, measured by AUC/C-index

Time frame: At baseline

Data from ClinicalTrials.gov

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