A single-center, cluster-randomized controlled trial was conducted to determine the effect of Sticker reminder intervention on IV-to-PO switching of fluoquinolone.
A single-center, cluster-randomized controlled trial was conducted across 44 general wards at Siriraj Hospital, Thailand, from July 2020 to December 2024. The study population consisted of adult patients who received at least one dose of intravenous fluoroquinolones. Wards were randomized in a 1:1 ratio to either the sticker reminder intervention or standard care. In the intervention group, a reminder sticker was applied to patients' vital signs sheets when predefined IV-to-oral switching criteria were met. The primary outcome was the proportion of intravenous-to-oral fluoroquinolone switching in the intention-to-treat (ITT) and modified intention-to-treat (mITT) populations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
168
a reminder sticker was applied to the vital signs sheet of patients meeting predefined switching criteria
Faculty of Medicine Siriraj Hospital
Bangkok, Bangkok, Thailand
IV-to-PO switching
Proportion of patients who underwent switching from intravenous fluoroquinolone to oral fluoroquinolone within the same hospitalization
Time frame: From the day of initiation of fluoroquinolone to the discharge date (Up to 1 year)
Length of stay
The total length of hospital stay of that given admission
Time frame: From the day of initiation of intravenous fluroquinolone to the day of discharge (up to 1 year)
Duration of FQ therapy
The total duration of intravenous fluroquinolone and oral fluroquinolone (day)
Time frame: From the first day to the last day of fluroquinolone use (up to 1 year)
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