This is a retrospective observational cohort study based on secondary use of routinely collected electronic health data. The design was selected to enable population-level characterisation of treatment patterns and clinical inertia (both diagnostic and therapeutic) in the management of hypertension across diverse settings in Brazil's public primary care system (SUS).
This is a retrospective observational cohort study based on secondary use of routinely collected electronic health data. The design was selected to enable population-level characterisation of treatment patterns and clinical inertia (both diagnostic and therapeutic) in the management of hypertension across diverse settings in Brazil's public primary care system (SUS). The retrospective cohort design allows for efficient use of existing clinical data to evaluate real-world practice against national guideline recommendations. The primary outcomes relate to treatment decisions and delays rather than interventional effects; therefore, an observational design is methodologically appropriate and ethically preferable. The study will be conducted across 05 Brazilian municipalities participating in the epHealth Primary Care Solutions platform. These municipalities span multiple regions and reflect heterogeneity in socio-demographic context, healthcare infrastructure, and epidemiological profiles.
Study Type
OBSERVATIONAL
Enrollment
15,000
Research Site
Florianópolis, Brazil
RECRUITINGUncontrolled blood pressure
Proportion of patients with uncontrolled blood pressure (BP ≥ 140/90 mmHg) who did not receive treatment intensification within 3 months of a recorded elevated BP.
Time frame: through study completion, an average of 1 year
Antihypertensive treatment
Proportions receiving monotherapy vs. combination therapy; distribution by pharmacologic class.
Time frame: through study completion, an average of 1 year
Risk stratification
Likelihood of treatment escalation stratified by low/moderate vs. high/very high CV risk.
Time frame: through study completion, an average of 1 year
AstraZeneca Clinical Study Information Center
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