This study aims to evaluate the safety and tolerability of JPI-547 in combination with irinotecan as a third-line and beyond therapy for recurrent or metastatic gastric cancer
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
49
The dose levels will be escalated following a 3+3 dose escalation scheme.
The dose levels will be escalated following a 3+3 dose escalation scheme.
Severance Hospital, Yonsei Cancer Center, Yonsei University College of Medicine
Seoul, South Korea
1b: dose-limiting toxicity rate
Time frame: The dose-limiting toxicity evaluation window is 28 days from C1D1.
phase 2: Overall Response Rate (ORR) according to RECIST v1.1
Time frame: At 6-week intervals through study completion, an average of 3 years.
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