Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy. Liposomal iron provided superior hematological improvement and gastrointestinal tolerance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
70
Oral liposomal iron capsules containing 17 iron per capsule, adminstered as 2 capsules daily, taken independently of meals for 6 months.
oral ferrous iron preparations (ferrous sulfate), each providing 100-200 mg elemental iron once daily, administered on an empty stomatch with 200 mg vitamin c for 6 months.
Goztepe Prof.Dr. Suleyyman Yalçın City Hospital
Istanbul, kadıköy, Turkey (Türkiye)
RECRUITINGChange in Hemoglobin Level From Baseline to Week 24
The change in hemoglobin concentration will be calculated as the absolute difference between baseline and week 24 values.
Time frame: 24 weeks
Change in Serum Ferritin Level From Baseline to Week 24
Absolute change in serum ferritin concentration from baseline to week 24.
Time frame: 24 weeks
Change in Transferrin Saturation (TSAT) From Baseline to Week 24
Absolute change in transferrin saturation percentage from baseline to week 24.
Time frame: 24 weeks
Change in Serum Iron Level From Baseline to Week 24
Absolute change in serum iron concentration from baseline to week 24.
Time frame: 24 weeks
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