Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age
descriptive, cross-sectional study analyzed baseline data from 40 children with DS and acute pneumonia enrolled prior to intervention in a larger trial. Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age.
Study Type
OBSERVATIONAL
Enrollment
40
Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age.
Badr university
Cairo, Egypt
RECRUITINGMona Mohamed Abdelkhalek
Cairo, Egypt
RECRUITINGserum IgG, IgA, IgM
Immunoglobulins: Concentrations of IgG(mg/dl) IgA,(mg/dl) and IgM (mg/dl) were determined from serum using an automated nephelometer
Time frame: Upon enrollment and prior to any intervention baseline data were collected
Respiratory Rate
Respiratory rate (breaths/minute) was determined by direct observation and counting of chest wall movements over one full minute
Time frame: Upon enrollment and prior to any intervention baseline data were collected
Arterial Oxygen Saturation (SaO2)
Peripheral oxygen saturation (%) was measured non-invasively via pulse oximetry
Time frame: Upon enrollment and prior to any intervention baseline data were collected
White Blood Cell count
Total WBC count (thousands/mm³) was measured from a whole blood sample using an ADVIA 120 automated hematology analyzer
Time frame: Upon enrollment and prior to any intervention baseline data were collected
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.