ICU Admission Diagnoses and ICU Mortality

Ataturk University1,248 enrolled

Overview

This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.

Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.

Study Type

OBSERVATIONAL

Enrollment

1,248

Conditions

Critical Illness Sepsis Septic Shock Acute Respiratory Distress Syndrome (ARDS)Acute Respiratory Failure Multiple Organ Dysfunction Syndrome

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients (≥18 years) admitted to the ICU between January 1, 2025 and December 31, 2025. * If a patient has more than one ICU admission during the study period, only the first ICU admission will be included. Exclusion Criteria: * ICU stay \<24 hours. * Missing essential data preventing assessment of the primary outcome (ICU mortality) and/or calculation of severity scores (APACHE II, SAPS, SOFA).

Locations (1)

Ataturk University

Erzurum, Turkey (Türkiye)

Outcomes

Primary Outcomes

ICU mortality

Death occurring during the index ICU stay (ICU mortality), abstracted from electronic medical records.

Time frame: From ICU admission until ICU discharge (end of index ICU stay), assessed up to 90 days

Secondary Outcomes

ICU length of stay (LOS)

ICU length of stay (days) during the index ICU admission, calculated as the difference between ICU admission and ICU discharge timestamps in the electronic medical record.

Time frame: From ICU admission to ICU discharge (index ICU stay), assessed at ICU discharge (up to 90 days)

ICU discharge disposition

Disposition at ICU discharge categorized as: death in ICU, transfer to hospital ward, or transfer to another facility; determined from the ICU discharge documentation in the electronic medical record.

Time frame: At ICU discharge (index ICU stay; assessed at the time of ICU discharge in the medical record, up to 90 days)

Data from ClinicalTrials.gov

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