to investigate whether oliceridine is safe and effective for induction of anesthesia by comparing henodynamic changes before and after endotracheal intubation with sufentanil
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
120
Oliceridine is diluted to a 1mg/kg injection solution
sufentanil is diluted to a 5μg/ml injection solution
Tangshan Maternal and Child Health Hospital
Tangshan, Hebei, China
blood pressure
Time frame: baseline, at the moment of intubation, right after intubation, 1 minute、3 minutes, and 5 minutes after intubation
heart beat
Time frame: baseline, at the moment of intubation, right after intubation, 1 minute、3 minutes, and 5 minutes after intubation
adverse reactions
Time frame: from the administration of sufentanil or oliceridine until discharge from the post-anesthesia care unit (PACU)
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