Cardiac Sympathetic Denervation in Patients With Refractory Arrhythmic Storm: a Single-center Case Series

Jose Manuel López González18 enrolled

Overview

The objective of our study was to evaluate the effectiveness of stellate ganglion block (SGB) and of the bilateral cardiac sympathetic denervation (BCSD) in patients with electrical storm refractory to conventional treatment..

A prospective, single-center observational study was designed with the aim of evaluate the safety and short-term efficacy of SGB within the first 24 hours, as well as the long-term effectiveness of ultrasound-guided percutaneous BCSD at 12 months, in patients with refractory electrical storm.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ventricular Arrhythmias Electrical Storm Stellate Ganglion Block

Interventions

Cardiac sympathetic denervation.PROCEDURE

Patients underwent stellate ganglion block with 10 ml of levobupivacaine 0.25% and subsequently ultrasound-guided percutaneous bilateral cardiac sympathetic denervation , two neuroablative lesions were created using conventional radiofrequency treatment at 60°C, 20 V for 90 seconds.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients over 18 years of age. * arrhythmic storm refractory to conventional treatment. Exclusion Criteria: * patients younger than 18 years of age. * previous history of heart transplantation. * history of previous surgical cardiac sympathetic denervation. * patients with neck anatomy considered unsuitable for the procedure (including previous neck surgery, burns, the presence of extensive scars, or large goiters with significant displacement of adjacent structures). * contraindications to the interventional technique (such as infection at the puncture site, or refusal to provide consent).

Locations (1)

FINBA

Oviedo, Principality of Asturias, Spain

Outcomes

Primary Outcomes

Arrhythmic burden.

The arrhythmic burden was quantified by the number of sustained ventricular arrhythmias, antitachycardia pacing (ATP) therapies, and ICD (implantable cardioverter-defibrillator) shocks recorded during the follow-up period.

Time frame: The arrhythmic burden was assessed both in the early period (first 24 hours following SGB) and in the long term (during the 12 months following BCSD).

Data from ClinicalTrials.gov

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