Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis

N/ANot Yet RecruitingNCT07383805

Assiut University81 enrolled

Overview

1. To investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients and its correlation with disease activity and inflammatory markers. 2. Association of Tim-3 with sacroiliac MRI findings and the hip inflammatory MRI scoring system (HIMRISS) .

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ankylosing Spondylitis AS Tim3

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Adult patients (\>18 years) diagnosed as AS according to 2009 ASAS -Classification criteria (8) Exclusion Criteria:-Age below 18 years old. Patients with other autoimmune diseases. infection (cause increase in inflammatory makers) Any patient with ferromagnetic implants or cardiac pacemaker pregnancy Uncontrolled Hypertension renal failure Chronic liver disease Malignancy Diabetes Mellitus

Locations (1)

Assiut university

Asyut, University, Egypt

Outcomes

Primary Outcomes

To investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients

investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients and its correlation with disease activity and inflammatory markers

Time frame: through study completion, an average of 1 year

Central Contacts

Eman Safwat, MD

CONTACT

01014116158 safwateman605@gmail.com

Data from ClinicalTrials.gov

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