Microenvironment in Patients Undergoing Non-traumatic Amputation

University of Aarhus20 enrolled

Overview

The microenvironment of the amputation stump in patients undergoing non-traumatic transfemoral amputation will be investigated with a combination of microdialysis and tissue sampling.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Lower Limb Amputation Above Knee

Interventions

ciNPWTDEVICE

Closed incision negative pressure wound therapy

SSDOTHER

Standard stump dressing

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria * 18 years or older * Cognitive ability to provide informed consent * Scheduled for transfemoral amputation at Aarhus University Hospital Exclusion criteria * Non-vascular indication of amputation * Already amputated on the contralateral leg * Insufficient flap perfusion * Allergic or sensitivity to silver or acrylic adhesives

Locations (1)

Aarhus University Hospital

Aarhus N, Denmark

RECRUITING

Outcomes

Primary Outcomes

Ischemia

Concentration of ischemic metabolites: Glucose, Lactate, Pyruvate and Glycerol

Time frame: Within 72 hours postoperatively

Data from ClinicalTrials.gov

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