Total Laparoscopic vs Open Pancreaticoduodenectomy for the Treatment of Periampullary Adenocarcinomas

Theodor Bilharz Research Institute30 enrolled

Overview

Laparoscopic pancreaticoduodenectomy (LPD), a surgical option for nonpancreatic periampullary adenocarcinoma (NPPA), is a complex procedure that has become increasing popular. However, there is no consensus as to whether this technique should be performed routinely. Our aim was to evaluate the outcomes of LPD compared with open pancreaticoduodenectomy (OPD).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Periampullary Carcinoma

Interventions

Conventional open pancreaticoduedectomyPROCEDURE

Fifteen patients in Group A had a traditional open pancreaticoduedectomy.

Total laparoscopic pancreaticoduedectomyPROCEDURE

Fifteen patients in Group A had a total laparoscopic pancreaticoduedectomy.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * • Body mass index \<28.0 kg/m2. * Ampullary tumors, duodenal tumors restricted to the second part of the duodenum, or lower common bile duct tumors. * Carefully confirmed resectability of the tumors based on preoperative radiology conducted by experienced radiologists and surgeons. Exclusion Criteria: * • Patients with \>180 degrees superior mesenteric artery encasement * Any celiac abutment. * Unreconstructable superior mesenteric vein/portal occlusion" Aortic invasion or encasement. * A history of previous upper abdominal surgery. * Tumors extending to the uncinate. * Severe cardiorespiratory comorbidities.

Locations (1)

Theodor Bilharz Research Institute

Giza, Egypt

Outcomes

Primary Outcomes

The incidence of pancreatic fistula after laparoscopic pancreaticoduodenectomy in comparison to open surgery

Laparoscopic pancreaticoduodenectomy is a complex procedure that has become increasing popular. However, there is no consensus as to whether this technique should be performed routinely. Our aim was to evaluate the outcomes of Laparoscopic pancreaticoduodenectomy compared with open pancreaticoduodenectomy.

Time frame: in 2 years between 2023 - 2025

Data from ClinicalTrials.gov

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