Hypotheses: We hypothesize that serum progesterone levels on the day of embryo transfer in HRT-FET cycles are positively associated with clinical pregnancy rates. Aims: To evaluate the relationship between serum progesterone levels on embryo transfer day and clinical pregnancy outcomes in frozen-thawed embryo transfer cycles using hormone replacement therapy (HRT). Primary outcome: To compare the incidence of clinical pregnancy outcome in those infertility patients undergoing frozen embryo transfer with caterized Progesterone level on the day of embryo transfer Secondary outcomes: Biochemical pregnancy rate. Implantation rate. Early pregnancy loss rate. Ectopic pregnancy rate.
Study Type
OBSERVATIONAL
Enrollment
370
The Chinese University of Hong Kong
Hong Kong, China
Clinical pregnancy rate (CPR)
Rate of clinical pregnancy outcome in subjects undergoing FET
Time frame: 6 weeks of gestation and ultrasound scanning will be performed to confirm at least one gestational sac around 1 to 3 months after FET
Biochemical pregnancy rate
Rate of biochemical pregnancy outcome in subjects undergoing FET
Time frame: Up to 12 weeks
Implantation rate
Rate of implantation in subjects undergoing FET
Time frame: Up to 12 weeks
Early pregnancy loss rate
Rate of early pregnancy loss in subjects undergoing FET
Time frame: Up to 12 weeks
Ectopic pregnancy rate
Rate of Ectopic pregnancy in subjects undergoing FET
Time frame: Up to 12 weeks
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