This study examined whether different types of exercise performed during hemodialysis sessions affect patients' health and quality of life. Patients receiving regular hemodialysis were assigned to resistance exercise, flexibility exercise, or usual care during dialysis. Changes in health-related outcomes were evaluated before and after the exercise period.
This single-center pilot study was conducted to explore the effects of exercise performed during hemodialysis on patients' health. Adult patients undergoing maintenance hemodialysis participated in one of three groups: resistance exercise, flexibility exercise, or usual care without exercise. The exercise programs were carried out during routine dialysis sessions under supervision. Patients' clinical measurements and self-reported health outcomes were assessed at the start of the study and again after completion of the exercise period. The study was carried out between December 2020 and April 2021 following approval by the institutional ethics committee.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
49
A structured resistance exercise program performed during routine hemodialysis sessions under supervision.
A structured flexibility and stretching exercise program performed during routine hemodialysis sessions under supervision.
Muğla Sıtkı Koçman University Training and Research Hospital
Muğla, Muğla, Turkey (Türkiye)
Change in dialysis adequacy assessed by Kt/V (urea)
Change in dialysis adequacy measured by single-pool Kt/V (urea).
Time frame: From baseline to 12 weeks
Change in dialysis adequacy assessed by urea reduction ratio (URR)
Change in dialysis adequacy measured by urea reduction ratio (URR), expressed as a percentage
Time frame: From baseline to 12 weeks
Change in Short Form-36 (SF-36) Health-Related Quality of Life score
Change in health-related quality of life assessed using the Short Form-36 Health Survey (SF-36), a validated 36-item questionnaire. SF-36 domain scores range from 0 to 100, with higher scores indicating better health-related quality of life.
Time frame: From baseline to 12 weeks
Change in Beck Depression Inventory score
Change in depressive symptoms assessed using the Beck Depression Inventory (BDI). Scores range from 0 to 63, with higher scores indicating more severe depressive symptoms.
Time frame: From baseline to 12 weeks
Change in body mass index (BMI)
Change in body mass index (BMI), calculated as weight in kilograms divided by height in meters squared (kg/m\^2). Higher BMI indicates greater body mass relative to height.
Time frame: From baseline to 12 weeks
Change in fat tissue index (FTI)
Change in fat tissue index (FTI) assessed by bioelectrical impedance analysis (BIA), calculated from fat tissue mass (FTM) normalized to height squared (kg/m\^2).
Time frame: From baseline to 12 weeks
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Change in lean tissue index (LTI)
Change in lean tissue index (LTI) assessed by bioelectrical impedance analysis (BIA), calculated from lean tissue mass normalized to height squared (kg/m\^2).
Time frame: From baseline to 12 weeks
Change in physical function assessed by the 6-minute walk test (6MWT)
Change in physical function assessed using the 6-minute walk test (6MWT), measured as the total distance walked in meters.
Time frame: From baseline to 12 weeks