This study aims to measure a blood protein called fibroblast activation protein (FAP), which is linked to tissue scarring and inflammation. A small blood sample will be taken from participants (RA , SSc patients and healthy people ), and the FAP level will be measured and compared with routine clinical examinations, imaging studies, and lung function tests. The purpose of this study is to improve understanding of disease activity and lung involvement in these conditions and to explore whether FAP could be useful as a blood marker for future patients. Participation in this study will not change the participant's usual medical care.
Study Type
OBSERVATIONAL
Enrollment
111
Sohag University Hospital
Sohag, Egypt
Serum fibroblast activation protein (FAP) concentration measured by ELISA in patients with rheumatoid arthritis and systemic sclerosis
Time frame: At baseline (Day 1)
disease activity
Correlation between serum FAP concentration and disease activity score in rheumatoid arthritis and systemic sclerosis
Time frame: baseline
pulmonary involvement
Correlation between serum FAP concentration and pulmonary involvement in patients with rheumatoid arthritis and systemic sclerosis
Time frame: baseline
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