This is a randomized, double-masked, placebo-controlled, dose-ranging, parallel-group, multi-center study designed to evaluate the safety and efficacy of GLK-321 in patients with Demodex blepharitis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
250
Twice daily administration of low dose GLK-321 to both eyes
Twice daily administration of mid dose GLK-321 to both eyes
Twice daily administration of high dose GLK-321 to both eyes
Glaukos Clinical Study Site
Newport Beach, California, United States
RECRUITINGPercentage of study eyes with elimination of collarettes
Percentage of study eyes that had eyelash collarettes due to Demodex blepharitis at the onset of treatment who demonstrate absence of collarettes after 6 weeks of treatment
Time frame: 6 weeks
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Once daily administration of high dose GLK-321 to both eyes
Twice daily administration of placebo to both eyes