Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease

University of Illinois at Chicago25 enrolled

Overview

This study examines the feasibility and acceptability of a mindfulness-based mobile intervention designed to support pain and sleep management among adolescents and young adults with sickle cell disease. Chronic pain and sleep problems are common in this population and can negatively affect daily functioning and quality of life. Participants will use a smartphone-based mindfulness program that includes structured modules and guided mindfulness exercises over an approximately 8-week period. The study aims to evaluate whether the intervention is feasible and acceptable for adolescents and young adults with sickle cell disease.

Study Type

INTERVENTIONAL

Allocation

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Chronic Pain Sickle Cell Disease Sleep Disturbance

Interventions

Participants receive a mindfulness-based mobile intervention designed to support symptom management related to pain and sleep. The intervention is delivered via a smartphone application and includes structured mindfulness content such as guided meditation and brief mindfulness exercises. Participants are asked to engage with the intervention over an approximately 8-week period. The study evaluates feasibility and acceptability.

Eligibility

Sex: ALLMin age: 15 YearsMax age: 39 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Individuals aged 15-39 years * Have been diagnosed with SCD * Are able to speak and understand English * Are able to complete questionnaires with minimal or no assistance from a caregiver * Report pain and/or sleep problems as assessed by the Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-Me) short forms * Have access to the internet on a smartphone, tablet, or computer Exclusion Criteria: * Individuals who have significant cognitive limitations that will impair their ability to use and understand the MBI, as per their health care provider or caregiver * Are currently receiving an MBI or have received more than 4 sessions of any MBI in the 6 months prior to the screening

Outcomes

Primary Outcomes

Participant retention rate

Percentage of enrolled participants who remain in the study through the 8-week intervention period

Time frame: At 8 weeks (post-intervention)

Attrition rate and reasons for withdrawal

Percentage of participants who withdraw from the study and documented reasons for withdrawal

Time frame: Throughout the 8-week intervention period

Weekly module completion rate

Percentage of assigned weekly modules completed by participants

Time frame: At 8 weeks (post-intervention)

Acceptability of the Mindfulness-Based Intervention

Acceptability of the digital mindfulness-based intervention assessed using a study-specific acceptability questionnaire. The questionnaire measures multiple dimensions including comfort level, effort required to engage, perceived fairness for patients with sickle cell disease, perceived effectiveness for pain and sleep management, clarity of intervention purpose, confidence in the intervention, interference with other priorities, and overall acceptability. The questionnaire uses 5-point rating scales for all items. The questionnaire also includes open-ended questions about device use, suggested improvements, and helpful and unhelpful aspects of the intervention.

Time frame: At 8 weeks (post-intervention)

Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes