This is a single-center, single visit study conducted in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria. The study is to develop a clinical photographic atlas to assess skin aging by studying the relationship between age, sun exposure and quantity of collagen measured non-invasively (LC-OCT). No product will be tested during the study.
Single-center, single visit study in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria. The study is to develop a clinical photographic atlas to assess skin aging by studying the relationship between age, sun exposure and quantity of collagen measured non-invasively (LC-OCT). No product will be tested during the study.
Study Type
OBSERVATIONAL
Enrollment
250
During the study visit, the investigator will for each subjects in Group 1: \- Perform standardized photographs using the ColorFace Group 2: \- Perform standardized photographs using the ColorFace Group 3: \- Perform standardized photographs using the ColorFace Group 4: * Perform standardized photographs using the ColorFace * Perform LC-OCT acquisitions on the forehead Group 5: * Perform standardized photographs using the ColorFace®; * Perform LC-OCT acquisitions on the forehead
Photographs
Image acquisition
CPCAD, Hôpital l'Archet 2
Nice, France
Non-invasive tissue imaging: 3D imaging through Line-field Confocal Optical Coherence Tomography technology (LC-OCT) acquisitions
Line-field Confocal Optical Coherence Tomography technology (LC-OCT) provides a unique 3D imaging modality, allowing the user to switch from a histology-like vertical mode to confocal-like horizontal mode and to record a 3D stack of tissue volumes in situ. With this technique skin can be imaged in vivo in its native state without further preparation. The superficial dermis can be clearly imaged using a live vertical, live horizontal and 3D mode. This assessment will be performed on the face (forehead) with the LC-OCT deepLive™ (DAMAE). This non invasive image will helps to characterize and quantify new metrics of skin aging linked to the dermal fibers network (collagen and elastin) such as caracterisation of the density and length of dermis fibers during aging.
Time frame: Day 1
Standardized photographs of the face (front and 45° left and right sides)
Standardized photographs of the face (front and 45° left and right sides) will be performed using the ColorFace (Newtone Technologies, Lyon, France). The ColorFace® has multiple lighting modes and can acquire up to 5 images in one setting from a user-definable shooting template without technician intervention. Subjects will be photographed using the following modalities: * Cross-polarized (polarizing filter angle: 90 degrees, no specular gloss on the skin surface and observation of color variations) * Standard 60 (polarizing filter angle: 60 degrees, observation of skin relief such as wrinkles) * No filter * Parallel-Polarized (polarizing filter angle: 0 degrees, observation of skin relief such as pores) * UV (observation of the pigmentation not visible to the naked eye). All the digital photographs will be identified by the protocol number, the SIN, the side photographed, the type of light used and anomyzed. They serve for illustration purposes of visible signs during skin aging .
Time frame: Day 1
Photo shooting
Photo shooting (Back and Front camera pictures) will be performed using an iPhone 15. Back camera pictures will be taken by a trained personnel and the front camera picture will be taken by the subject himself after a brief training by the study personnel. These photos will serve for grading facial aging: Comparing the clinical assessments made by three dermatologists with those obtained by an AI-based scoring system that analyses selfie pictures.
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photo from back and front camera pictures and selfie
Time frame: Day 1
Questionnaire
Subjects will be asked to complete a self-assessment questionnaire about their lifestyle habits in order to assess the link between lifestyle habits and aging.
Time frame: Day 1