ASMact: Study on Management of Bronchial Asthma

Meyer Children's Hospital IRCCS500 enrolled

Overview

Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.

Patients aged 6 to 17 years presenting to the emergency department with an acute asthma exacerbation were included. Clinical outcomes were compared between a pre-intervention period (October 2024-May 2025) and a post-intervention period (October 2025-May 2026). Between the two study periods, a structured educational intervention targeting medical and nursing staff was implemented. The intervention consisted of didactic lectures, clinical simulation sessions, case-based discussions, and the dissemination of updated diagnostic and therapeutic flowcharts based on the 2025 Global Initiative for Asthma (GINA) guidelines.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Asthma Acute Asthma Childhood Asthma in Children Asthma Crisis

Eligibility

Sex: ALLMin age: 6 YearsMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 6 and 17 years * Presentation to the emergency department with a diagnosis of acute asthma exacerbation * Evaluation in the emergency department of one of the participating centers during the study periods Exclusion Criteria: * Age \< 6 years or \> 17 years * Diagnosis other than acute asthma exacerbation * Incomplete or missing clinical data * Patients transferred from other hospitals already treated for the same episode * history of allergy to any drugs used in the protocol

Locations (2)

Arcispedale S. Anna

Ferrara, FE, Italy

RECRUITING

Meyer Children's Hospital IRCCS, Firenze

Florence, Italy

RECRUITING

Outcomes

Primary Outcomes

Change in the number of correctly reported diagnoses before and after intervention

Assessment of adherence to guideline-based diagnostic and therapeutic management of pediatric patients presenting with acute asthma exacerbations in the emergency department.