Outcomes of Single Anastomosis Sleeve Jejunal Bypass (SAS-J) VS Sleeve Gastrectomy

Ain Shams University80 enrolled

Overview

The aim of this work is to compare the outcomes of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with sleeve gastrectomy as regards efficacy including sustained weight loss, metabolic syndrome, quality of life, complications and associated comorbidities in morbid obese.

The most commonly performed bariatric surgery worldwide is the vertical sleeve gastrectomy (VSG), the Roux-en-Y gastric bypass (RYGB), and the One anastomosis (Mini) gastric bypass, which has been demonstrated to produce excellent bariatric and metabolic outcomes. Single anastomosis sleeve ileal (SASI) bypass was introduced in 2015 as a modification of Santorini's operation in, as it keeps pass to the duodenum so the biliary tree and the whole gut and can be assessed by the endoscope; there are no blind loops, excluded segments or foreign bodies.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Single Anastomosis Sleeve Jejunal Bypass Sleeve Gastrectomy

Interventions

Single anastomosis sleeve jejunal bypassPROCEDURE

Patients underwent single anastomosis sleeve jejunal bypass as a metabolic and weight loss surgery.

Laparoscopic sleeve gastrectomyPROCEDURE

Patients underwent laparoscopic sleeve gastrectomy (LGS) as a metabolic and weight loss surgery.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients age from 18 to 60 years old. * Both sexes. * Patients with body mass index (BMI) ≥ 40. * Patients with BMI (35 - 40) with obesity related comorbidities. (e.g. type 2 diabetes mellitus, obstructive sleep apnea, hypertension, hyperlipidemia, obesity hypoventilation syndrome, non-alcoholic fatty liver disease, gastroesophageal reflux disease and severe arthritis). * Able to be committed to follow-up. Exclusion Criteria: * Patients underwent previous Bariatric surgeries. * Patients with severe systemic disease, such as congestive heart failure - unstable angina - recent stroke or myocardial infarction less than 3 months ago. Contraindications for insufflation as those with severe cardiovascular or severe restrictive respiratory diseases. * Patients that refused to participate in the study. * Patients with psychiatric illness. * Preoperative upper GI endoscopy findings of GERD class C and Barrett's oesophagus * Previous upper GIT surgery or liver cirrhosis. * Patients on oral steroid therapy. * Not fit for general anaesthesia (e.g. patients with severe heart disease or untreatable coagulopathies). * Significant abdominal adhesions. * Major psychiatric illness. * Pregnant patients.

Locations (1)

Ain Shams University

Cairo, Egypt

Outcomes

Primary Outcomes

Weight loss

Weight loss was recorded.

Time frame: 1 month after the procedure

Secondary Outcomes

Metabolic syndrome

Metabolic syndrome was recorded.

Time frame: 1 month after the procedure

Assessment of quality of life

quality of life was assessed using specific scoring system is a variation of the BAROS (Bariatric Analysis and Reporting Outcome System). The specific tiers you listed (High, Moderate, and Mild Improvement) * High Improvement excess Weight Loss (%EWL) \>50% + comorbidity resolution + no complications. * Moderate Improvement EWL 30-50% + partial comorbidity resolution. * Mild Improvement EWL \<30% + no major issues.

Time frame: 1 month after the procedure

Incidence of complications

Incidence of complications such as gastroesophageal reflux disease (GERD), bile reflux, gall stones, reoperations, and postoperative bleeding were recorded.

Time frame: 1 month after the procedure

Data from ClinicalTrials.gov

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